clear jar filled with mesotherapy injection solution


Published March 8, 2023

Mesotherapy is a medical treatment that has been used for decades to rejuvenate skin, reduce the appearance of wrinkles, and improve the overall texture of the face. This revolutionary technique can be used to target specific areas of the body and provide long-lasting results. In this guide, we'll explore what mesotherapy is, its origins, how it works, its benefits and cost, and alternative treatments.


Developed as a medical procedure in 1952 by French Doctor, Michel Pistor, mesotherapy involves injecting small amounts of medications, vitamins, homeopathics and other ingredients just below the surface of the skin to provide targeted treatments. Mesotherapy was originally invented to treat osteoarthritis and muscle pain. The technique was then introduced in the field of aesthetic medicine to improve skin quality. It can be used to combat aging effects by reducing wrinkles and sagging, creating smoother skin textures with improved hydration levels, and increasing collagen fibers for firmer skin tones; or it can also target areas that are prone to stubborn pockets of fat buildup—giving you more clearly defined contours. With so much potential offered from this unique treatment option, let's take a closer look at how mesotherapy works!


Mesotherapy is a non-invasive procedure in which small doses of medications are administered into the skin to treat a range of conditions from wrinkles and cellulite to hair loss and scarring. It was developed as an alternative to traditional medicine. The medication used in mesotherapy is typically composed of hyaluronic acid, vitamins, minerals, amino acids, enzymes, hormones and other revitalizing ingredients (also called biostimulators) that help to stimulate skin cells so that they can work more effectively.

Mesotherapy treatments involve multiple injections into the targeted area using a very fine needle. Depending on your goals and individual needs, your doctor may use different types of medications or adjust the dosage accordingly. During treatment sessions you may experience some discomfort but most patients report feeling no pain at all due to the needles being so small. 

A complete mesotherapy treatment program comprises an average of three to four sessions, with intervals of between 15 days to one month. A maintenance session is then recommended every two to three months.


By providing cells with the nutrients they need to function properly, mesotherapy stimulates cell metabolism and increases the production of collagen, elastin, and hyaluronic acid. It improves skin regeneration, hydration and, more globally, skin quality. Mesotherapy is recommended to prevent skin aging and also to smooth, firm, and restore skin radiance. It can also be used in combination with topical products and other procedures such as laser treatments or microneedling for even better results!  


The cost of mesotherapy will vary depending on your individual needs, but typically runs anywhere from $500-$2,000 per session depending on how much product your doctor uses during treatment. Most people need at least three to four sessions spaced out over several months for optimal results so keep this in mind when budgeting for your treatment plan.


While both mesotherapy and botulinum toxin treatments aim to improve the appearance of the skin, they have different methods of achieving this goal. Mesotherapy injections involve a series of small injections that are targeted at specific areas of the face or body. These injections contain a mixture of vitamins, minerals, and other nutrients that are designed to nourish and rejuvenate the skin. On the other hand, botulinum toxin injections work by paralyzing the muscles that cause wrinkles. Overall, both treatments can be effective, but it's important to understand the differences to determine which one is right for you.


Laboratoires FILORGA developed NCEF [New Cellular Encapsulated Factors], a unique complex with encapsulated active ingredients used in mesotherapy injections: hyaluronic acid, amino acids, vitamins, coenzymes, minerals, and antioxidants.

NCEF is incorporated into our core formulas to fight the signs of skin aging. To go even further and make the most of its expertise, Laboratoires FILORGA created the NCEF collection of regenerating skincare containing NCEF with ingredients incorporated in concentrations comparable to those used in meso-injections(1), for action on wrinkles, firmness, and radiance. For even a faster action, FILORGA has developed NCEF-SHOT, the serum with the highest concentration of NCEF to be used as a 10-day treatment.


Mesotherpay is a safe non-invasive procedure that can provide long-lasting results when performed correctly by a qualified professional. It can be used to treat a variety of conditions from wrinkles and cellulite to hair loss and scarring with minimal downtime necessary afterwards. However, it does come at a cost so it's important to budget accordingly if you're considering this type of treatment option for yourself! Additionally, there are topical alternatives developed by Laboratoires FILORGA depending on your individual needs.

(1) Effectiveness of a cosmetic product with a formula containing 50 ingredients in concentrations comparable to those used in one meso-injection. Meso-injection originally developed by FILORGA. Excluding NCEF-ESSENCE.